Molecular genetic pathology is the subspecialty of medical genetics and genomics and pathology in which the principles, theory, and technologies of molecular biology and molecular genetics are used to make or confirm clinical diagnoses of Mendelian genetic disorders, disorders of human development, immunologic conditions, infectious diseases, and malignancies; to assess the natural history of those disorders; and to provide the primary physician with information by which to improve the ability to provide optimal care for individuals affected with these disorders. Molecular genetic pathology includes a body of knowledge and techniques necessary to study diseases associated with alterations in the genome; provides information about gene structure, function, and alteration; and applies laboratory techniques for the diagnosis, treatment, and prognosis of individuals with these disorders.